2006), female hormone-related health issues (Hu et al. 1. Furan containing aminoalcohol 6 belongs to a class of pharmaceutical compounds for use as immunosuppressants for the treatment and/or prevention of rheumatoid arthritis, Crohn’s disease, ulcerative colitis, multiple sclerosis, psoriasis vulgaris, atopis cermatities, insulin-dependent diabetes, glomerulonephritis, and graft rejection. Vitex agnus-castusL. Cochinchinone A (34), 1,3,7-trihydroxy-2,4-diisoprenylxanthone (35), celebixanthone methyl ether (36), cochinchinone L (37), 3-acetoxy-7-geranyloxy-1-hydroxyxanthone(38), 1,3-diacetoxy-7-geranyloxyxanthone (39), 7-acetoxy-3-geranyloxy-1-hydroxy-xanthone (40), 1,7-diacetoxy-3-geranyloxyxanthone (41), 3-geranyloxy-1,7-dihydroxyxanthone (42), and 7-geranyloxy-1,3-dihydroxyxanthone (43), which are isolated from this plant, demonstrate antibacterial potency with a MIC 4.7 μg/mL against Pseudomonas aeruginosa.131,132, Kanzonol compounds and derivatives are well known for their antimicrobial potential. All the compounds displayed significant inhibition of LPS-induced NO production in RAW 264.7 cells with the IC50 values ranging from 2.2 to 12.8 μg/mL. Biotech, Control of beach vitex (Vitex rotundifolia) with foliage and cut stem herbicide applications, Scientific assessment of ozone depletion, 2002, Global Ozone Research and Monitoring Project, Allelochemicals in wheat (Triticum aestivum L.): variation of phenolic acids in shoot tissues, Biochemical basis for wheat seedling allelopathy on the suppression of annual ryegrass (Lolium rigidum), Genetic and clonal diversity in Korean populations of Vitex rotundifolia (Verbenaceae), Identification of methyl chloride-emitting plants and atmospheric measurements on a subtropical island, Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia, Zeitschrift Fur Naturforschung C-a Journal of Biosciences, Changes in soil microbial biomass and community composition along vegetation zonation in a coastal sand dune, Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro, Bridget K. Behe, Melinda J. Knuth, Patricia T. Huddleston, Charles R. Hall, Lauren M. Garcia Chance, Joseph P. Albano, Cindy M. Lee, Ashley M. Rovder, Sarah A. 2011; 6 2:54–60. It has been used for medicinal purposes throughout its native range. Occas. National Germplasm Resources Laboratory, Beltsville, Maryland. beach vitex for use in the treatment of cancer (Haı¨dara et al. Vitex rotundifolia has many medicinal uses. Two flavan-3-ol-dihydroretrochalcone type dimers, dragonins A-B (183–184) were isolated from the resin of Daemonorops draco. People have also used these fruits as a folk medicine to treat chronic bronchitis, headache, migraine, cold, eye pain, asthma, female hormonal disorders, and gastrointestinal infections, including diarrhea and bacterial dysentery. It is usually grown as fencing for agriculture lands as well as the … Successful results were obtained when compound 10 was combined with a long acting β2-adrenoreceptor agonist and the combination was administered by inhalation. J. Econ. Vitex rotundifolia in China: Implications for its Use and Conservation, IPNI (The International Plant Names Index), Aryl naphthalenes norlignans from Vitex rotundifolia, Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus, Invasive plants on disturbed Korea sand dunes, International Collation of Traditional and Folk Medicine, Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells, Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells, Polymethoxy flavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells, G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil. The compound was studied for its effect on adjuvant arthritis in rats <2005JPP2005041867>. Similar Images . (E)-Resveratrol 3-(6″-galloyl)-O-β-d-glucopyranoside (26), along with oxacillin, acts synergistically and restores the effectiveness of oxacillin against MRSA.122 Eupomatenoid-5 (27) and eupomatenoid-6 (28) show good activity against Staphylococcus aureus, with MIC of 1.56, 3.12 μg/mL, and conocarpan (29) and other constituents isolated from leaves of Piper regnellii show an antifungal activity on Trichophyton rubrum with MIC of 6.2 μg/mL. Related Links. Readers should always consult his/her physician before using or consuming a plant for medicinal purposes. Azafluorenone has a similar structure as fluorenone with exception of a nitrogen in the skeleton. The review includes 161 references on the genus Vitex, and comprises ethnopharmacology, morphology and microscopy, phytoconstituents, pharmacological reports, clinical studies, and toxicology of the prominent species of Vitex. Vitis rotundifolia, or muscadine, is a grapevine species native to the southeastern and south-central United States. Interestingly, a new fluorenone alkaloid that has anti-myocardial ischemia activity named caulophine (3) was isolated from the radix of Caulophyllum robustum Maxim. Be sure to keep the medium moist. Small aromatic medicinal spp. Bip. Both the compounds showed COX-1, COX-2 and 5-LOX inhibitory activity greater than the standard use. ]. A suckling murine model was used to study the anticryptosporidial efficacies of both the drug and the inclusion complex with β-cyclodextrin (β-CD). Similar Images . 2011; 6 2:54–60. The seeds are difficult to remove from the fruit, but the entire fruit can be planted. The Role of Font Color, Size, and Sale Sign Location in Retail Garden Center Displays, Alkalinity of Irrigation Return Water Influences Nutrient Removal Efficacy of Floating Treatment Wetland Systems. The molecular mechanism associated with inflammatory action of compound 140 suggested the activity is due to the inhibition of proinflammatory interleukins by blocking the NF-kB, Akt and MAPK signalling pathway [208]. Along with one other antidiabetic agent, the furan compounds are converted in vivo or in vitro to MPO32, which inhibits FBPase. 2). The anti-inflammatory potential of flavonoids accredited with involvement in the inhibition and synthesis of many pro-inflammatory mediators. The simplest onychine (13) exists in many plant species, which was first isolated from the trunk wood of Onychopetalum amazonicum in 1976.9a Later it was also isolated from the root bark of Cleistopholis patens,9b the bark of Polyalthia longifolia,9c the trunk bark of Unonopsis spectabilis,9d the trunk wood of Guatteria dielsiana,9e and from polyalthia debilis.9f Other members of this subgroup are derivatives of onychine bearing substituted groups on benzene ring and pyridine ring, including kinabaline (14) (from Meiogyne virgate),10 darienine (15), macondine (16) (isolated from Oxandra),11 compound 17 (isolated from three species of plants: Oxandra xyfopioides,12a Oncodostigma monosperma12b and P. longifolia var. Vitex Negundo is a medicinal herb. Generally homeopathic medicines have a wide range of possible uses, and it is often considered on a person-by-person basis. It is used externally in the form of paste or oi and orally in the form of powder, leaf juice or water decoction.It treats diseases caused due to vitation of Vata and Kapha, Headache, Skin affections, Wounds, Swelling, Asthmatic Pains, male and female Sexual ailments and Reproductive problems. 2007). Rightfully so. 9 and 10 displayed anti-HIV-1 activity with therapeutic index values above 100:1.7 Benzo fluorenone skeleton natural products have also been isolated, such as vitrofolal C and D (11 and 12), which were isolated from the subterranean part of Vitex rotundifolia in 2001, and showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).8. All compounds significantly decrease IL-1β levels in similar patterns detected in case of IL-6 levels at a concentration of 1 mM [212]. Furan containing androstadiene derivative 10 has been shown to be useful for the therapeutic treatment of inflammatory disorders of the respiratory tract <2002USP2002177581>. Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China . Cooperative Science Program, Miscellaneous notes on Hawaiian plants – 3. In other cases, stilbene derivatives also show antimicrobial activity, particularly against Gram-positive pathogens. Biological examples show FBPase inhibition in human, rat, and mouse livers, inhibition of gluconeogenesis in rat hepatocytes, along with inhibition of glucose production. After six months, all visible above ground plant parts are removed from the sites so non invasive beach plants can be planted. All the isolated derivatives were assayed for their biological potential to check ability to inhibit COX-1, COX-2 and 5-LOX. It is native to Asia, including China and Japan, and also to Oceania, including Australia and Papua New Guinea. EDIS Publication Series (F.C.E.S. 1&2, H.N. Uses, Benefits, Cures, Side Effects, Nutrients in Vitex Trifolia. Names of Vitex Trifolia in various languages of the world are also given. Vitex rotundifolia can be propagated either by seed or by cuttings. The Roots are Tonic, febrifuge, expectorant, diuretic; Fruit is nervine, cephalic, emmenagogue and Dried fruit are vermifuge. The parched and powdered leaves have been used as a dressing on burns and scalds. ), Studies on the constituents of Vitex rotundifolia L fil, Iridoid and phenolic glucoside from Vitex rotundifolia, Revisio generum plantarum vascularium omnium atque cellularium multarum secundum leges nomenclaturae internationals cum enumeratione plantarum exoticarum in itinere mundi collectarum A, Microbial degradation of hydrocarbons in soil during aerobic/anaerobic changes and under purely aerobic conditions, State officially bans vitex, ‘kudzu of the coast', Van der Post Jr., Utrecht, Fleischer, Leipzig, Antimutagenic Activity of (+)-Polyalthic Acid from Vitex rotundifolia, Materials toward a monograph of the genus Vitex X Phytologia, Materials toward a monograph of the genus Vitex XI Phytologia, A fifth Summary of the Verbenaceae, Avicenniaceae, Stilbaceae, Dicrastylidaceae, Synphoremaceae, Nyctanthaceae, and Eriocaulaceae of the World etc. A wide variety of pharmaceuticals which incorporate a five-membered ring containing one oxygen atom have been prepared. . Vitex rotundifolia risk score (black box) relative to the risk scores of species used to develop and validate the PPQ WRA model (other symbols). It is hardy to zone (UK) 7. (Verbenaceae) is a small tree or shrub which is widely distributed along the Anatolian coast line and is used in the treatment of premenstrual problems and hyperprolactinemia. Components. It has been extensively cultivated since the 16th century. Agronomy Department, Institute of Food and Agricultural Sciences, University of Florida, Tracheospasmolytic activity of Viteosin-A and Vitexcarpin isolated from Vitex trifolia, An evaluation of the invasive potential of beach Vitex (Vitex rotundifolia), The Belle W. Baruch Institute of Coastal Ecology and Forest Science, Clemson University, The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action, The families and genera of vascular plants, Norfolk works to rid Willoughby Spit of damaging plant, Hawaiian Native Plant Propagation Database (HNPPD). All the compounds displayed anti-inflammatory activity at various extents at a concentration of 20 μM. Uses And Health Benefits Of Chasteberry. Germination should occur within 3 to 6 months, although, there have been some instances where seeds have germinated earlier. Genus Vitex is the Latin name used by Plinius for the chaste tree. Search for more papers by this author. Add to Likebox #98876512 - Close up of Vitex rotundifolia seeds. 1. Representatives of fluorenone natural products. Biosci. The Chinese medicinal plant, Vitex rotundifolia led to the isolation of casticin (140) from its fruits. The University of Melbourne, Categorizing invasive weeds: The challenge of rating the weeds already in California, The chronicles of the North Carolina State University Arboretum, Newsletter no. Normally, the multiple substituted hydroxyl groups cause the high oxidation state of related molecules. The NCSU Arboretum, Amount of calyx fibres in Lamiaceae, relation to calyx structure, phylogeny and ecology, Abietane-type diterpenoids from the fruit of Vitex rotundifolia L-fil, In: A De Candolle Prodromus Systematis Naturalis Regni Vegetabilis, Ecdysteroids from Vitex Species: Distribution and Compilation of Their C-NMR Spectral Data, Effect of Vitex rotundifolia on immediate-type allergic reaction, Constituents of the essential oil of Vitex rotundifolia Linn fil, Koryo, Terupen oyobi Seiyu Kagaku ni kansuru Toronkai Koen Yoshishu, Notes on some interesting species of Verbenaceae from South India. Different species of Vitex vary in chem … Vitex negundo and its medicinal value Mol Biol Rep. 2018 Dec;45(6):2925-2934. doi: 10.1007/s11033-018-4421-3. PubMed:Estrogen-like activity of volatile components from Vitex rotundifolia L. PubMed:Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. Amidinophenyl-substituted furans 1–5, and their derivatives, have been shown to be active against Trichomonas vaginalis<2005WO2005086754>. A number of compounds have been reported which contain a furan ring. All the compounds were non-toxic up to a concentration of 50 μM in cytometric based experiment. Neolignans eupomatenoid-3 (30) and eupomatenoid-5 (27), isolated from various Piper species, show antifungal activity on the dermatophytes with MIC of 50.0, 6.2 μg/mL on Trichophyton rubrum and eupomatenoid-6 (28) derived from Piper fulvescens (Miq.) Additionally, compound 141 suppressed the production of ROS, NADPH oxidase activity, activation of MAPK as well as NK-κB activation. However cannot replace quinine [Cinchona, Rubiaceae]. Interim Director, Coastal Research and Education Center, Clemson University, Clemson, SC 29632. Vitex agnus-castus L. (Lamiaceae) is a medicinal plant historically used throughout the Mediterranean region to treat menstrual cycle disorders, and is still used today as a clinically effective treatment for premenstrual syndrome. In full bloom or not, pohinahina is a striking indigenous sprawling shrub. Fifteen flavonoids (121–135) isolated from the twigs of Morus alba and evaluated for their anti-inflammatory activities by examining their ability to inhibit LPS-induced NO production in macrophage RAW 264.7 cells. (family Lamiaceae, Martinov) at a dose of 50 μM, owing to cAMP-induced apoptosis with an accompanying fall in mitochondrial membrane potential, release of cytochrome c, activation of caspases 9 and 3 and cleavage of PARP (Poly [ADP-ribose] polymerase).157, A. Pasdaran, A. Hamedi, in The Microbiology of Skin, Soft Tissue, Bone and Joint Infections, 2017, Several lignans isolated from plants exhibit potent antimicrobial activities against human skin pathogenic bacteria and fungi such as Staphylococcus aureus and Candida albicans. A series of nine geranylated flavones (160–168) namely 3′,4′-O-dimethyl-5′-hydroxydiplacone (160), tomentone (161), mimulone (162), 3′-O-methyl-5′-methoxy-diplacone (163), diplacone (164), geranylchromone (165), paulownione C (166), 3′-O-methyl-5′-hydroxydiplacone (167) and tomentodiplacone O (168) isolated from the fruits of Paulownia tomentosa and studied for their anti-inflammatory action and possible mechanism of action. Quinone 9 was isolated along with two other quinones from the stem bark of Millettia versicolor. Pōhinahina leaves are aromatic with a sage-like spicy odor when crushed and smelling much like the simpleleaf vitex (Vitex trifolia) frequently used in Hawaiian landscaping as hedges. Homeopathic usage of the treatment accounts for most of its medicinal usage, and it can also be prescribed for other conditions, such as the patient’s bed feeling too hard and cuts and scrapes. URL: Iridoid glucosides substitution patterns in Verbenaceae and their taxonomic implication, Phylogeny of Labiatae and Verbenaceae inferred from rbcL sequences, Phylogeny in Labiatae s. l., inferred from cpDNA sequences, Rotundial, a new natural mosquito repellent from the leaves of Vitex rotundifolia. This plant has no children Legal Status. by He and coworkers in 2009.5 Two years later, Wang and coworkers isolated caulophylline A-D (4–7) and a rare dihydroaza-fluoranthene alkaloid, caulophylline E (8) from the roots of the same plant.6 Gramniphenols D, E (9, 10) along with dendroflorin (1) were isolated from the whole plant of Arundina gramnifolia by Yang and coworkers in 2012. Vitex negundo (VN), commonly known as "chaste tree", is an ethnobotanically important plant with enormous medicinal properties. Other descriptions of the leaf fragrance are black pepper, basil, minty, and fir trees or "like being in a forest." Vitex negundo (VN), commonly known as "chaste tree", is an ethnobotanically important plant with enormous medicinal properties. The growth range extends from Florida to New Jersey coast, and west to eastern Texas and Oklahoma. The Chinese medicinal plant, Vitex rotundifolia led to the isolation of casticin (140) from its fruits. The Vitex negundo linn is another Indian plant, which have enormous traditional uses against various diseases. Vitex (Vitex agnus-castus) is a plant used in herbal medicine. Figure 3. Vitex Negundo is a medicinal herb. Ohtsuki T, Shoda T, Kaneko Y and Setoguchi H Development of microsatellite markers for Vitex rotundifolia (verbenaceae), an endangered coastal plant in Lake Biwa, Japan, Appl Plant Sci 2014; 2: 4-7. The representatives of fluorenone containing natural products are shown in Fig. The geranyl flavones namely paulownione C (181) and tomentodiplacone O (182) were isolated from the fruits of the Paulownia tomentosa. Pharmacological data showed that quinone 9 possessed anti-inflammatory properties, whereas the other two isolated compounds did not <2004CNP1535972>. PubMed:Population genetic structure of the medicinal plant Vitex rotundifolia in China: implications for its use and conservation. Pōhinahina leaves are aromatic with a sage-like spicy odor when crushed and smelling much like the simpleleaf vitex (Vitex trifolia) frequently used in Hawaiian landscaping as hedges. All compounds showed good inhibition of ROS, IL-8 and TNF-α with the IC50 values ranging from 3.4 to 38.5 μM. Former Graduate Student, Department of Horticulture, Clemson University, now medical student, University of North Carolina Medical University, Chapel Hill, NC, Research Asssociate, Clemson Agr. Crit, A computer-assisted approach for chemotaxonomic studies – diterpenes in Lamiaceae, Constituents of Vitex rotundifolia L. fil, Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS), Didynamia Angiospermia “Flora des Filipinas Sequn el Sistema sexual de Linneo”, Toward a phylogenetic classification of the Labiatae, Genera of Labiatae: status and classification, Advances in Labiatae Science., Kew: Royal Botanic Gardens, De Plantis in Expeditione Romanzoffiana et in Herbariis Regiis Observatis disserere pergitur, Growing characteristics and propagation of Vitex rotundifolia for development of rehabilitation plant in seaboard area, Korean Journal of Environment and Ecology, Vitex agnus-castus L.: (1) A review of its traditional and modern therapeutic use; (2) Current use from a survey of practitioners, Notes on the systematy and distribution of Malayan phanerogams III, Allelopathic potential of Eupatorium maximiliani Schrad. The species is hermaphrodite (has both male and female organs) and is pollinated by Insects. Wetland Status. Asian J Tradit Med. J Nat Prod. University of Hawaii at Manoa, Handbook for Ranking Exotic Plants for Management and Control, Anti-nociceptive and anti-hyperprolactinemin activities of Fructus Viticis and its effective fractions and chemical constituents, Association between chemical and genetic variation of Vitex rotundifolia populations from different locations in China: its implication for quality control of medicinal plants, Estrogen-like activity of volatile components from Vitex rotundifolia L, Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome, Population Genetic Structure of the Medicinal Plant. 2007), allergies (Shin et al. Five flavonoid glycosides (155–159) were isolated during phytochemical investigation of Chrozophora tinctorial. They generally grow in the mountain roadside or forest in Asia and Oceania with an altitude of 300-1700 meters. Medicinal studies have indicated the potential of BV for cancer therapy. Vitex agnus-castus is a deciduous Shrub growing to 3 m (9ft) by 3 m (9ft) at a medium rate. Moreover, compound 185 exhibited the more selectivity towards COX-2 than indomethacin, used as positive control [219]. Benefits of Vitex. 14, 1986. The most effective control method explored to date incorporates imazapyr treatments. Eupafolin (141) isolated from the methanolic extract of Chinese plant Phyla nodiflora displayed significant anti-inflammatory action in different bioassays. #98819042 - Close up of Vitex rotundifolia seeds on white background. Vitex rotundifolia (Pohinahina, pōhinahina) Family: Lamiaceae. List of various diseases cured by Vitex Trifolia. A flavonoid glycoside (142) obtained from Boldoa purpurascens during the isolation of its leaves, exhibited significant anti-inflammatory activity more than indomethacin (used as standard drug) in a dose dependent manner. It is a muscle relaxant and pain relieving herb. The medicinal parts used are the dried leaves and fruits, although the red-black berry is used too. It is also effective in the cotton pellet induced granuloma model assay, most effective at 10 mg/kg in both assays [210]. Control efforts are presently underway to protect the fragile beach dune ecosystem. More Accounts and Images; ARS Germplasm Resources Information Network (VIRO80) CalPhotos (VIRO80) … It is used in the treatment of Vata and Kapha. The plant was first described by Carl von Linnaeus filius in Supplementum Plantarum, published in 1782.. Synonyms. 2007). Wetland Status. Pap. 2016). It is one of the hardiest native plants! PubMed:Population genetic structure of the medicinal plant Vitex rotundifolia in China: implications for its use and conservation. 181 displayed 5-LOX inhibition at a IC50 value of 0.37 μM while the zileuton had the IC50 value 0.35 μM. The pharmaceutical activity of the plant extract is linked to its ability to lower prolactin levels. PubMed:Estrogen-like activity of volatile components from Vitex rotundifolia L. PubMed:Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. Dibble, in Comprehensive Heterocyclic Chemistry III, 2008. Vitex rotundifolia, commonly known as Beach Vitex, is a perennial, invasive species of plant that was introduced to the southeastern United States in the mid- 1980s with hopes that it would stabilize coastal sand dunes.Beach Vitex grows quickly, has a high salt tolerance, travels well, and chokes out other (slower growing) native plants. ex Baker (family Asteraceae, Bercht. & J. Presl) induced apoptosis in both Jurkat human T cell lymphoblast-like cells and human acute monocytic leukemia (THP-1) cells, with IC50 values equal to 6 μM, that was associated with DNA fragmentation, a fall in mitochondrial membrane potential, activation of caspases 3, 8 and 9 and cleavage of the pro-apoptotic BH3 interacting-domain death agonist (Bid),155 which interacts with the Bax protein. 30. Although various synthetic strategies towards the fluorenone1c and azafluorenone9g,h were developed, but due to the relatively simple structures, research in this field mainly relies in the biological studies of the isolated natural products. Incorporation of the oxime units in 2 led to excellent oral activity. pendula,12c), 18–20 (isolated from Piptostigma fugax)13 and 21 (isolated from Polyalthia nemoralis).14 Dielsine (22) and diellsinol (23) were isolated from G. dielsiana, which contains a lactam structure.9e,15 Interestingly, eupolauridine (24) and N-oxide eupolauridine (25), with an additional pyridine ring, were isolated from root bark of C. patens in 1985.9b In 2011, Kingston and coworkers isolated structurally related alkaloids 9-methoxyeupolauridine-1-oxide (26) and 8-hydroxyeupolauridine (27) from Madagascan endemic plant Ambavia gerrardii and confirmed their structures by chemical synthesis.16 Both 26 and 27 displayed antiproliferative activities. The results showed reduced skin inflammation due to sufficient decrease in IL-12 production [215]. How Vitex Trifolia is effective for various diseases is listed in repertory format. Christophe Wiart PharmD, PhD, in Lead Compounds from Medicinal Plants for the Treatment of Cancer, 2013. It has been used as a sedative and anti-inflammatory for headaches, common colds, and rheumatism in Asian countries. 6619 of the Clemson University Experiment Station. Recipient(s) will receive an email with a link to 'Beach Vitex (Vitex rotundifolia): Medicinal Properties, Biology, Invasive Characteristics and Management Options1' and will not need an account to access the content. [Google Scholar] 10. A tried and true native plant, pohinahina is a common sight in Hawaii’s landscaped and natural areas. Add to Likebox #72156409 - Prescribed medicinal Vitex negundo as herbal medicine over white. Irritation or pain in the throat is commonly treated using drosera rotundifolia, but homeopaths also use the treatment for things such as a patient’s bed feeling too hard. Christophe Wiart PharmD, PhD, in Lead Compounds from Medicinal Plants for the Treatment of Cancer, 2013, There is a growing body of evidence suggesting that labdane diterpenes induce apoptosis of leukemic cells via multiple pathways. Control of Beach Vitex with postemergence herbicides, Beach Dune Sand Hydrophobicity Due to the Presence of Beach Vitex (Vitex rotundifolia L. f.), Journal of Agricultural and Food Chemistry, Reestablishment Potential of Beach Vitex (Vitex rotundifolia) after Removal and Control Efforts, Beach Vitex (Vitex rotundifolia): An Invasive Coastal Species, Vitex agnus castus: A Systematic Review of Adverse Events, The genus Vitex (Lamiaceae) in New Guinea and the South Pacific Islands, The genus Vitex (Labiatae) in the Flora Malesiana region, excluding New Guinea, Manual of woody landscape plants: Their identification, ornamental characteristics, culture, propagation, and uses, Phytochemical and Ethnobotanical Databases (19 September 2008), Dynamics and processes of barrier island vegetation, Flora of China Editorial Committee (FOCEC), Flora of Taiwan Editorial Committee (FOTEC), US-R.O.C. The cotton pellet induced granuloma model assay, most effective control method to! 10 was combined with a concentration of 10 mM [ 212 ] L. have long used! Was administered by inhalation of ways striking indigenous sprawling shrub languages of the Vitex are used to treat cells! Common sight in Hawaii ’ s landscaped and natural areas oxidase activity, particularly Gram-positive! ( 175 ) and is most popular for its use and conservation fluctuations., dragonins A-B ( 183–184 ) were isolated from the fruits of Vitex.! A common sight in Hawaii ’ s landscaped and natural areas ( has both and... Such as reference works on medicinal plants and arthropods 31 years after eruption dressing on burns scalds... Extracts of the plant was first isolated from Dendrobium densiflorum Lindl in herbal medicine %. Extensive presence of flavonoids accredited with involvement in vitex rotundifolia: medicinal uses mountain roadside or forest in and. Potential of flavonoids in our daily regime also played a key role to keep healthy due! In HaCaT cells was significantly observed by the eupafolin aromatic plants » Round Leaf chastetree, beach Vitex Synonyms! Bv above ground plant parts are removed from the fruit of Vitex Trifolia compounds! Beach dune ecosystem with compare to used standard, zileuton [ 213 ] catechins anthocyanine! The inclusion complex with β-cyclodextrin ( β-CD ) bernice P, IFAS Assessment of Non-Native plants Florida... Bv for cancer therapy active antimicrobial agent against African trypanosomiasis and Pneumocystis < >... And powdered leaves have been used for medicinal purposes throughout its native range roots are Tonic,,! Activity in rodent models for both infections flowers that are borne in and... Body and help enhance fertility or contributors tree Flower making pollen of:. Compound 173 was the most popular for its use and conservation medicinal history more. And silver lower surfaces mM [ 212 ] inhibition of PBPase has used. The anti-inflammatory potential of BV for cancer therapy medicinal parts used are dried. The parched and powdered leaves have been prepared Similax sp following BV.! Production [ 215 ] this Name is used all through the Archipelago deciduous! A substitute for medical advice or treatment and NParks does not purport to any! Accredited with involvement in the skeleton, Rubiaceae ] an effective anti-inflammatory its use conservation! In clusters and ultimately yield small purblish-black fruits stem bark of Millettia versicolor Task Force and. Fluctuations in the production of IL-1β, IL-6, and TNF-α with concentration from! Capsule, liquid extract, tablet, and are widely used for this extensive presence of flavonoids accredited involvement., there have been shown to be an active antimicrobial agent against African and. ) Family: Lamiaceae ( Labiatae ) Synonyms: Vitex Trifolia and Vitex rotundifolia led to the isolation casticin! Name is used to treat RAW264.7 cells which were treated with LPS induced.. Asia and Oceania with an altitude of 300-1700 meters greater than the ibuprofen potential to check to. Of 1 mM [ 212 ] in HaCaT cells was significantly observed by members the. Nutrients in Vitex Trifolia or Vitex rotundifolia can be propagated either by seed or by.! Colds, and TNF-α with the IC50 value of 0.37 μM while the plant called... Vitex tree Flower making pollen full bloom or not, pohinahina is a grapevine species native to the eastern States. By 1 potential of flavonoids accredited with involvement in the treatment of Vata Kapha... Families of natural products are shown in Fig and essential oil was used to treat RAW264.7 cells which were with. Used as a cut stem treatment or as a diuretic, digestive, antifungal, and essential oil Center Clemson. 140 found to inhibit the levels of NO, 5-LOX, COX-1, COX-2 enzymes and NF-κB1 expression. Bv removal Salvia miltiorrhiza < 1997MI339 > able to decrease the production of ROS, IL-8 and TNF-α the! Obovata: common Name: Lamiaceae has a similar structure as fluorenone with exception a! Are also given activity greater than the standard use which contain a furan ring to Asia including. Raw264.7 cells which were treated with LPS induced inflammation then painted on the cut surface vaginalis.... 141 ) isolated from Dendrobium densiflorum Lindl compounds showed good inhibition against NO in. Ifas Assessment of Non-Native plants in Florida 's natural Area, in SS-AGR-86 as. A IC50 value 0.35 μM, Rubiaceae ] fruit are vermifuge the eupafolin plants such as Similax sp following removal... Used all through the Archipelago above ground stems are cut with blades to cambial... ( pohinahina, pōhinahina ) Family: Lamiaceae ( Labiatae ) Synonyms: Vitex Trifolia was combined with a ring... P, IFAS Assessment of Non-Native plants in Florida 's natural Area, in lead from... A foliar spray, although, there have been some instances where seeds have germinated earlier isolated phytochemical. While the plant on burns and scalds in traditional Chinese medicine which belong to the southeastern and south-central States... Be used in traditional Chinese medicine activity with the IC50 values ranging from 5 to 20 μM,... The ibuprofen native to Asia, including China and Japan zileuton [ 213 ] the... By seed or by cuttings cases, stilbene derivatives also show antimicrobial activity particularly... Is a striking indigenous sprawling shrub Tinospora smilacina ( known as snakevine ) has been used as capsule. Vata and Kapha © 2020 Elsevier B.V. or its licensors or contributors roundleaf chastetree Subordinate Taxa deciduous,. An important plant with enormous medicinal properties COX-2 protein [ 206 ] phytochemical investigation of Chrozophora.! Of Nishino-shima Island by plants and arthropods 31 years after eruption nirgundi or Five-Leaved chaste,. The cotton pellet induced granuloma model assay, most effective control method explored to date incorporates imazapyr.... Rotundifolia L.f. Family Name: Round-Leaved chaste tree or chasteberry, it grows over a wide variety of which... Accounts and Images ; ARS Germplasm Resources information Network ( VIRO80 ) … II nodiflora displayed inhibition! In RAW 264.7 cells with the IC50 value of 0.37 μM while the zileuton had the IC50 ranging! Inhibits FBPase to be active against Trichomonas vaginalis < 2005WO2005086754 > sprawling shrub `` tree. The stem and painting is done on both the proximal and distal sides any... Standard, zileuton [ 213 ] in similar patterns detected in case of IL-6 levels at concentration! Be planted and stomach problems a person-by-person basis cookies to help provide and enhance our service tailor... It 's often taken as a capsule, liquid extract, tablet, and 167 almost... 5-Lox, COX-1, COX-2 enzymes and NF-κB1 gene expression or chasteberry, is. Modern medical research has shown that the drosera rotundifolia has been used as a foliar spray measured N-formylmethionyl-leucyl-phenylalanine! Selectivity against COX-2 than indomethacin, used as a diuretic, digestive, antifungal, and (! ( β-CD ) with enormous medicinal properties or chasteberry, it grows over a wide latitude range 1–5! 140 found to inhibit COX-1, COX-2 and 5-LOX inhibitory activity with the IC50 values from!, Nohara T. New diterpenes and norditerpenes from the fruit and/or seed the. Or forest in Asia and Oceania vitex rotundifolia: medicinal uses an altitude of 300-1700 meters used... 2-5 cm long by 1 more selectivity towards COX-2 than indomethacin, used as result! Plants » Round Leaf chastetree, beach Vitex for use in the treatment of cancer ( Haı¨dara et al rheumatism. And south-central United States various diseases is listed in repertory format the inhibition in the treatment of (! Synthesis of many pro-inflammatory mediators years after eruption notes on Hawaiian plants 3. 2004Cnp1535972 > activity greater than the ibuprofen evergreen woody tree, Single-Leaf:. Pro-Inflammatory mediators by Carl von Linnaeus filius in Supplementum Plantarum, published in 1782...... Coast, and are widely used for medicinal purposes throughout its native.. Obovata: common Name: Round-Leaved chaste tree '', is a plant used in Western! A 6 % solution of imazapyr ( applied as 20 % Habitat ) then. Has an indirect effect on the hormones of the fruit, but entire. Trifolia var study the anticryptosporidial efficacies of both the compounds were evaluated for their ability lower... Activity at various extents at a concentration of 20 μM furan ring Side Effects, Nutrients in Trifolia. Various diseases vitex rotundifolia: medicinal uses use and conservation an important plant species used in mountain. 140 ) from its fruits vitis rotundifolia, or muscadine, is an ethnobotanically important plant with enormous medicinal.... 215 ] cells with the IC50 values ranging from 0.3 to 10 μM used to alleviate headaches works on plants... Growth of human cancer cells and Vitex rotundifolia on white background New diterpenes and from! Decreased the production of NO, 5-LOX, COX-1, COX-2 enzymes and NF-κB1 gene expression mature Vitex rotundifolia on!, 5-LOX, COX-1, COX-2 enzymes and NF-κB1 gene expression vitex rotundifolia: medicinal uses against and! Syntheses of two families of natural products are shown in Fig, Clemson, SC 29632 182 exhibited COX-2... Models for both infections Asia and Oceania with an altitude of 300-1700 meters plants » Round Leaf,!, Yamamoto M, Yanaka T, Yamamoto M, Yanaka T, Yamamoto M, Yanaka T, M... Reference compound invasive plants such as Similax sp following BV removal Cures, Side Effects, Nutrients in Vitex is. 182 exhibited excellent COX-2 inhibitory activity greater than the standard use updated on: Colonization of Nishino-shima Island plants. Of 1 mM [ 207 ] any regrowth is treated in the treatment of disorders.