Foods That Contain Psoralen. The lemon is a very healthy fruit that is loaded with vitamin C and fiber. Do not use different formulations of bioflavonoids at the same time without first talking to your doctor. This problem cannot be solved by the use of mandarins as the parental line (see Rough, Rangpur and Volkamer lemons progenies) because they all contain limettin and sometimes oxypeucedanin hydrate (Fig 8). These are fine in the shade, but if you get them on your skin and then go into sunlight, they turn into nasty skin irritants. Furanocoumarins irreversibly inhibit a cytochrome P450 metabolizing enzyme called CYP3A4, as stated above. As shown in our study the levels of furanocoumarins in celery, celeriac, parsnip, carrot, lemon and The citrus fruit peels often contain chemicals called furanocoumarins and psoralens. Store bioflavonoids at room temperature away from moisture and heat. Aug. 19, 2008 -- Grapefruit, orange, and apple juices block drugs commonly used to treat infections, allergy, transplant rejection, cancer, and high blood pressure. CYP3A4 is a metabolizing enzyme for almost 50% of drugs, and is found in the liver and small intestinal epithelial cells. Regardless of the determination step used, the repeatability of the measurements (expressed as RSD) did not exceed 10%. If your condition does not improve, or if it appears to get worse, contact your doctor. Furanocoumarins are a specific group of secondary metabolites that commonly present in higher plants, such as citrus plants. The pericarp and whole fruit of C. grandis "Tormentosa" were found to contain up to 17 coumarins and furanocoumarins (Kuo et al., 2017;Li et al., 2014;Tian et al., 2019). Scroll down this page to view a list of foods that are rich in psoralen, a compound that has been used in the treatment of psoriasis, vitiligo and eczema.Psoralens are naturally occurring substances that belong to a group of compounds known as furocoumarins. The major furanocoumarins found in grapefruits (Citrus paradisi) include bergamottin, epoxybergamottin, and 6′,7′-dihydroxybergamottin.During biosynthesis of these furanocoumarins, coumarins undergo biochemical modifications corresponding to a prenylation … bergamottin (LOD = 0.01µgg−1) in citrus fruits because this furanocoumarin is unstable under GC conditions. As shown in our study the levels of furanocoumarins in celery, celeriac, parsnip, carrot, lemon and other foods obtained at a retail market varied over a wide range; the highest contents were determined in parsnip, while the levels of these toxins in carrots and citrus pulps were relatively low. Grapefruit juice contains furanocoumarins. 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